BDBM50288531 Benzo[1,3]dioxol-5-yl-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-acetic acid methyl ester::CHEMBL103362

SMILES COC(=O)C(C1c2ccccc2CCc2ccccc12)c1ccc2OCOc2c1

InChI Key InChIKey=YRFGKNFBHATPQQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288531   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288531(Benzo[1,3]dioxol-5-yl-(10,11-dihydro-5H-dibenzo[a,...)
Affinity DataIC50: 2.50E+4nMAssay Description:Compound was tested for its ability to inhibit Endothelin A receptor induced arachidonic acid release(AARA) in rabbit renal artery vascular smooth mu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288531(Benzo[1,3]dioxol-5-yl-(10,11-dihydro-5H-dibenzo[a,...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of binding of [125I]ET1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article