BDBM50288331 4-(7,8-Difluoro-3-trifluoromethyl-5H-isothiochromeno[4,3-c]pyrazol-1-yl)-benzenesulfonamide::CHEMBL97059

SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(c2SCc3cc(F)c(F)cc3-c12)C(F)(F)F

InChI Key InChIKey=IFWCFNSNAXCZCB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50288331   

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288331(4-(7,8-Difluoro-3-trifluoromethyl-5H-isothiochrome...)
Affinity DataIC50: 2.67E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288331(4-(7,8-Difluoro-3-trifluoromethyl-5H-isothiochrome...)
Affinity DataIC50: 2.67E+3nMAssay Description:Inhibition of COX-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

LigandPNGBDBM50288331(4-(7,8-Difluoro-3-trifluoromethyl-5H-isothiochrome...)
Affinity DataIC50: 6nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

LigandPNGBDBM50288331(4-(7,8-Difluoro-3-trifluoromethyl-5H-isothiochrome...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article