BDBM50288326 8-Fluoro-1-(4-methanesulfonyl-phenyl)-7-methoxy-3-trifluoromethyl-1,5-dihydro-isothiochromeno[4,3-c]pyrazole::CHEMBL96110

SMILES COc1cc2CSc3c(nn(c3-c2cc1F)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=NHGLUMVRJDITTP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50288326   

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288326(8-Fluoro-1-(4-methanesulfonyl-phenyl)-7-methoxy-3-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

LigandPNGBDBM50288326(8-Fluoro-1-(4-methanesulfonyl-phenyl)-7-methoxy-3-...)
Affinity DataIC50: 75nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2014
Entry Details Article

LigandPNGBDBM50288326(8-Fluoro-1-(4-methanesulfonyl-phenyl)-7-methoxy-3-...)
Affinity DataIC50: 75nMAssay Description:Inhibition of Prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article