BDBM50288302 CHEMBL4162590

SMILES CNCC(O)COc1ccc(cc1)S(=O)(=O)NCCc1ccccc1

InChI Key InChIKey=ORXFXBSFIHMCRN-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50288302   

TargetCarbonic anhydrase 12(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288302(CHEMBL4162590)
Affinity DataKi:  40nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288302(CHEMBL4162590)
Affinity DataKi:  59nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288302(CHEMBL4162590)
Affinity DataKi:  75nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288302(CHEMBL4162590)
Affinity DataKi:  146nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288302(CHEMBL4162590)
Affinity DataKi:  2.69E+4nMAssay Description:Displacement of [3H]-CGP12177 from human beta1 ADR expressed in HEK293T cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288302(CHEMBL4162590)
Affinity DataKi:  3.98E+4nMAssay Description:Displacement of [3H]-CGP12177 from human beta2 ADR expressed in HEK293T cell membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed