BDBM50288294 3-(4-Methanesulfonyl-phenyl)-2-phenyl-spiro[3.4]oct-2-en-1-one::CHEMBL90988

SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)C11CCCC1)c1ccccc1

InChI Key InChIKey=VWIZNMROODLCAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288294   

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288294(3-(4-Methanesulfonyl-phenyl)-2-phenyl-spiro[3.4]oc...)
Affinity DataIC50: 500nMAssay Description:Inhibition of PGE-2 production in arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288294(3-(4-Methanesulfonyl-phenyl)-2-phenyl-spiro[3.4]oc...)
Affinity DataIC50: 12nMAssay Description:Inhibition of PGE-2 production by arachidonic acid-stimulated CHO cells expressing human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article