BDBM50288182 CHEMBL4167473

SMILES CCNCC(O)COc1ccc(cc1)C(=O)NCCc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=MMGSKTDLKZYECG-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50288182   

TargetCarbonic anhydrase 12(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288182(CHEMBL4167473)
Affinity DataKi:  1.90nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288182(CHEMBL4167473)
Affinity DataKi:  9.30nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288182(CHEMBL4167473)
Affinity DataKi:  22nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288182(CHEMBL4167473)
Affinity DataKi:  49nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288182(CHEMBL4167473)
Affinity DataKi: <1.00E+5nMAssay Description:Displacement of [3H]-CGP12177 from human beta1 ADR expressed in HEK293T cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288182(CHEMBL4167473)
Affinity DataKi: <1.00E+5nMAssay Description:Displacement of [3H]-CGP12177 from human beta2 ADR expressed in HEK293T cell membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed