BDBM50288043 CHEMBL78853::N-(4-Bromo-3-methyl-isoxazol-5-yl)-3,4-dimethoxy-benzenesulfonamide

SMILES COc1ccc(cc1OC)S(=O)(=O)Nc1onc(C)c1Br

InChI Key InChIKey=FDPWJZSWHSXSLF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288043   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288043(N-(4-Bromo-3-methyl-isoxazol-5-yl)-3,4-dimethoxy-b...)
Affinity DataIC50: 2.40E+4nMAssay Description:Binding affinity against human Endothelin B receptor in transfected COS 7 cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288043(N-(4-Bromo-3-methyl-isoxazol-5-yl)-3,4-dimethoxy-b...)
Affinity DataIC50: 490nMAssay Description:Binding affinity against human Endothelin A receptor in TE 671(ATCC# HTB 139) cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article