BDBM50288027 Biphenyl-4-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide::CHEMBL311258

SMILES Cc1noc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)c1C

InChI Key InChIKey=SZJKGOUNLCLNNW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288027   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288027(Biphenyl-4-sulfonic acid (3,4-dimethyl-isoxazol-5-...)
Affinity DataIC50: 610nMAssay Description:Binding affinity against human ETB receptor in transfected COS 7 cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288027(Biphenyl-4-sulfonic acid (3,4-dimethyl-isoxazol-5-...)
Affinity DataIC50: 9.90E+3nMAssay Description:Binding affinity against human ETA receptor in TE 671(ATCC# HTB 139) cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article