BDBM50288024 CHEMBL78080::N-(4-Bromo-3-methyl-isoxazol-5-yl)-benzenesulfonamide

SMILES Cc1noc(NS(=O)(=O)c2ccccc2)c1Br

InChI Key InChIKey=WAIXPTZIWAKDPT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50288024   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288024(N-(4-Bromo-3-methyl-isoxazol-5-yl)-benzenesulfonam...)
Affinity DataIC50: 2.00E+4nMAssay Description:Binding affinity against human Endothelin B receptor in transfected COS 7 cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288024(N-(4-Bromo-3-methyl-isoxazol-5-yl)-benzenesulfonam...)
Affinity DataIC50: 79nMAssay Description:Binding affinity against human Endothelin A receptor in TE 671(ATCC# HTB 139) cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288024(N-(4-Bromo-3-methyl-isoxazol-5-yl)-benzenesulfonam...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was tested for binding affinity against Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288024(N-(4-Bromo-3-methyl-isoxazol-5-yl)-benzenesulfonam...)
Affinity DataIC50: 2.51E+3nMAssay Description:Compound was tested for binding affinity against Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article