BDBM50288007 CHEMBL311138::N-(4-Bromo-3-methyl-isoxazol-5-yl)-2,5-diethyl-benzenesulfonamide

SMILES CCc1ccc(CC)c(c1)S(=O)(=O)Nc1onc(C)c1Br

InChI Key InChIKey=OSBWUJAIYSBBKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288007   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288007(N-(4-Bromo-3-methyl-isoxazol-5-yl)-2,5-diethyl-ben...)
Affinity DataIC50: 5.20E+3nMAssay Description:Binding affinity against human Endothelin B receptor in transfected COS 7 cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288007(N-(4-Bromo-3-methyl-isoxazol-5-yl)-2,5-diethyl-ben...)
Affinity DataIC50: 6.20nMAssay Description:Binding affinity against human Endothelin A receptor in TE 671(ATCC# HTB 139) cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article