BDBM50287993 CHEMBL80532::N-(3,4-Dimethyl-isoxazol-5-yl)-2,5-dimethyl-benzenesulfonamide

SMILES Cc1noc(NS(=O)(=O)c2cc(C)ccc2C)c1C

InChI Key InChIKey=PJUGXSRKEDNLKM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287993   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287993(N-(3,4-Dimethyl-isoxazol-5-yl)-2,5-dimethyl-benzen...)
Affinity DataIC50: 5.80E+4nMAssay Description:Binding affinity against human Endothelin B receptor in transfected COS 7 cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287993(N-(3,4-Dimethyl-isoxazol-5-yl)-2,5-dimethyl-benzen...)
Affinity DataIC50: 270nMAssay Description:Binding affinity against human Endothelin A receptor in TE 671(ATCC# HTB 139) cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article