BDBM50287992 5-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-2-propyl-benzenesulfonamide::CHEMBL311781

SMILES CCCc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1C

InChI Key InChIKey=XWNXSAKNQIGGHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287992   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287992(5-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-2-propyl-be...)
Affinity DataIC50: 2.60E+4nMAssay Description:Binding affinity against human Endothelin B receptor in transfected COS 7 cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287992(5-Bromo-N-(3,4-dimethyl-isoxazol-5-yl)-2-propyl-be...)
Affinity DataIC50: 16nMAssay Description:Binding affinity against human Endothelin A receptor in TE 671(ATCC# HTB 139) cell membrane preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article