BDBM50287954 (E)-3-[(2S,5R)-5-(4-Chloro-6-methoxy-3-methyl-pyrazolo[3,4-b]quinolin-1-yl)-2,5-dihydro-furan-2-yloxy]-1-phenyl-propenone::CHEMBL176954

SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@@H]1O[C@H](O\C=C\C(=O)c2ccccc2)C=C1

InChI Key InChIKey=ZKFCOWKXCRPYQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287954   

TargetGTPase HRas(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287954((E)-3-[(2S,5R)-5-(4-Chloro-6-methoxy-3-methyl-pyra...)
Affinity DataIC50: 3.50E+4nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article