BDBM50287947 (E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyrazolo[3,4-b]quinolin-1-yl)-4-(2-nitro-phenylsulfanyl)-morpholin-2-yl]-but-2-enoic acid ethyl ester::CHEMBL299877

SMILES CCOC(=O)\C=C\C[C@@H]1CN(C[C@@H](O1)n1nc(C)c2c(Cl)c3cc(OC)ccc3nc12)Sc1ccccc1[N+]([O-])=O

InChI Key InChIKey=UPDISUVQPKSYEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287947   

TargetGTPase HRas(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287947((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...)
Affinity DataIC50: 1.60E+4nMAssay Description:In vitro for inhibition of nucleotide exchange process of oncogenic RasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article