BDBM50287798 4-(2-{(R)-2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-propyl}-thiazol-5-yl)-butyric acid::CHEMBL72168

SMILES C[C@H](Cc1ncc(CCCC(O)=O)s1)NCC(O)c1cccc(Cl)c1

InChI Key InChIKey=LULIDPWYMOAXGN-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287798   

TargetBeta-1 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287798(4-(2-{(R)-2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylam...)
Affinity DataKi:  6.40E+3nMAssay Description:Compound was tested for its binding affinity against Beta-1 adrenergic receptor in CHO cell membrane using [125I]iodocyanopindolol as the radioligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-2 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287798(4-(2-{(R)-2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylam...)
Affinity DataKi:  1.39E+4nMAssay Description:Compound was tested for its binding affinity against beta2 adrenergic receptor in CHO cell membrane using [125I]iodocyanopindolol as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-3 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287798(4-(2-{(R)-2-[2-(3-Chloro-phenyl)-2-hydroxy-ethylam...)
Affinity DataKi:  3.65E+4nMAssay Description:Compound was tested for its ability to stimulate adenylyl cyclase activity in CHO Beta-3 adrenergic receptor cell membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article