BDBM50287795 3-{2-[(R)-2-((S)-2-Hydroxy-3-phenoxy-propylamino)-propyl]-thiazol-5-yl}-propionic acid::CHEMBL73220

SMILES C[C@H](Cc1ncc(CCC(O)=O)s1)NC[C@H](O)COc1ccccc1

InChI Key InChIKey=RADSZQZWYHKGEG-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287795   

TargetBeta-3 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287795(3-{2-[(R)-2-((S)-2-Hydroxy-3-phenoxy-propylamino)-...)
Affinity DataEC50:  2.76E+3nMAssay Description:Compound was tested for its ability to stimulate adenylyl cyclase activity in CHO Beta-3 adrenergic receptor cell membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-2 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287795(3-{2-[(R)-2-((S)-2-Hydroxy-3-phenoxy-propylamino)-...)
Affinity DataKi:  1.23E+3nMAssay Description:Compound was tested for its binding affinity against beta2 adrenergic receptor in CHO cell membrane using [125I]iodocyanopindolol as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-1 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287795(3-{2-[(R)-2-((S)-2-Hydroxy-3-phenoxy-propylamino)-...)
Affinity DataKi:  3.44E+3nMAssay Description:Compound was tested for its binding affinity against Beta-1 adrenergic receptor in CHO cell membrane using [125I]iodocyanopindolol as the radioligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-3 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287795(3-{2-[(R)-2-((S)-2-Hydroxy-3-phenoxy-propylamino)-...)
Affinity DataKi:  3.53E+3nMAssay Description:Compound was tested for its binding affinity against beta3 adrenergic receptor in CHO cell membrane using [125I]iodocyanopindolol as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article