BDBM50287585 CHEMBL4169775

SMILES CC(=O)N[C@@H](COCc1ccccc1)C(=O)N[C@H](CCc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)NO

InChI Key InChIKey=BZUDGKQASYWREU-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287585   

TargetMacrophage metalloelastase(Human)
University of California-Riverside

Curated by ChEMBL
LigandPNGBDBM50287585(CHEMBL4169775)
Affinity DataKd: <50nMAssay Description:Binding affinity to recombinant human MMP12 catalytic domain (Gly106 to Gly26 residues) expressed in Escherichia coli BL21 codon plus by 1D 1H alipha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
University of California-Riverside

Curated by ChEMBL
LigandPNGBDBM50287585(CHEMBL4169775)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human MMP12 catalytic domain (Gly106 to Gly26 residues) expressed in Escherichia coli BL21 codon plus using Mca-Pro-Leu-Gly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
University of California-Riverside

Curated by ChEMBL
LigandPNGBDBM50287585(CHEMBL4169775)
Affinity DataKd: <50nMAssay Description:Binding affinity to recombinant human MMP12 catalytic domain (Gly106 to Gly26 residues) expressed in Escherichia coli BL21 codon plus by 2D [15N,1H] ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
University of California-Riverside

Curated by ChEMBL
LigandPNGBDBM50287585(CHEMBL4169775)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human MMP12 catalytic domain (Gly106 to Gly263 residues) expressed in Escherichia coli BL21 Codon Plus cells using 5-FAM/QX...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed