BDBM50287424 CHEMBL418697::[(2R,4S)-2-Benzyl-1-(3,5-bis-trifluoromethyl-benzoyl)-piperidin-4-yl]-carbamic acid 3-dimethylamino-propyl ester

SMILES CN(C)CCCOC(=O)N[C@H]1CCN([C@H](Cc2ccccc2)C1)C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=KBVPOFHEUMGKGC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287424   

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287424([(2R,4S)-2-Benzyl-1-(3,5-bis-trifluoromethyl-benzo...)
Affinity DataIC50: 11nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article