BDBM50287396 CHEMBL40189::N-[(2R,4S)-2-Benzyl-1-(3,5-dichloro-benzoyl)-piperidin-4-yl]-2,2,2-trifluoro-N-quinolin-4-ylmethyl-acetamide

SMILES FC(F)(F)C(=O)N(Cc1ccnc2ccccc12)[C@H]1CCN([C@H](Cc2ccccc2)C1)C(=O)c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=TVPMJLYGHVNXLV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287396   

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287396(N-[(2R,4S)-2-Benzyl-1-(3,5-dichloro-benzoyl)-piper...)
Affinity DataIC50: 600nMAssay Description:Compound was tested for inhibition of NK1 receptor from gerbil midbrain; NT means not testedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article