BDBM50287384 (R)-N*1*-[(S)-1-(5,6-Dichloro-1H-benzoimidazol-2-yl)-3-methyl-butyl]-N*4*-hydroxy-2-isobutyl-succinamide::CHEMBL42311

SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](CC(C)C)c1nc2cc(Cl)c(Cl)cc2[nH]1

InChI Key InChIKey=YZOKWMYHTLQIDP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287384   

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287384((R)-N*1*-[(S)-1-(5,6-Dichloro-1H-benzoimidazol-2-y...)
Affinity DataIC50: 68nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287384((R)-N*1*-[(S)-1-(5,6-Dichloro-1H-benzoimidazol-2-y...)
Affinity DataIC50: 33nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287384((R)-N*1*-[(S)-1-(5,6-Dichloro-1H-benzoimidazol-2-y...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article