BDBM50287377 (R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(6-trifluoromethyl-1H-benzoimidazol-2-yl)-butyl]-succinamide::CHEMBL289513

SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](CC(C)C)c1nc2ccc(cc2[nH]1)C(F)(F)F

InChI Key InChIKey=QVXRAVFETVTALN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287377   

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287377((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287377((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287377((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-3-methyl-1-(...)
Affinity DataIC50: 10nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article