BDBM50287375 (R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-3-methyl-butyl]-2-isobutyl-succinamide::CHEMBL298033

SMILES CC(C)C[C@H](CC(=O)NO)C(=O)N[C@@H](CC(C)C)c1ncc[nH]1

InChI Key InChIKey=TUXGRLPRNXNACO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287375   

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287375((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-3-...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287375((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-3-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287375((R)-N*4*-Hydroxy-N*1*-[(S)-1-(1H-imidazol-2-yl)-3-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article