BDBM50287195 1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-5-ylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL28779

SMILES OC(=O)c1c(Sc2ccc3OCOc3c2)c2ccccc2n1Cc1ccc2OCOc2c1

InChI Key InChIKey=LTMNIPISSYOICK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287195   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287195(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50: 4.50E+3nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287195(1-Benzo[1,3]dioxol-5-ylmethyl-3-(benzo[1,3]dioxol-...)
Affinity DataIC50: 380nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin A recep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article