BDBM50287194 5,6-Dimethoxy-1-(7-methoxy-benzo[1,3]dioxol-5-ylmethyl)-3-(3-methoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL416570

SMILES COc1cccc(Sc2c(C(O)=O)n(Cc3cc4OCOc4c(OC)c3)c3cc(OC)c(OC)cc23)c1

InChI Key InChIKey=MNLRNQODLJLCSB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287194   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287194(5,6-Dimethoxy-1-(7-methoxy-benzo[1,3]dioxol-5-ylme...)
Affinity DataIC50: 1.10E+3nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287194(5,6-Dimethoxy-1-(7-methoxy-benzo[1,3]dioxol-5-ylme...)
Affinity DataIC50: 58nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin A recep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article