BDBM50287193 1-Benzo[1,3]dioxol-5-ylmethyl-6-benzyloxy-5-methoxy-3-(3,4,5-trimethoxy-phenylsulfanyl)-1H-indole-2-carboxylic acid::CHEMBL435568

SMILES COc1cc(Sc2c(C(O)=O)n(Cc3ccc4OCOc4c3)c3cc(OCc4ccccc4)c(OC)cc23)cc(OC)c1OC

InChI Key InChIKey=UWDFQTODSZRCKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287193   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287193(1-Benzo[1,3]dioxol-5-ylmethyl-6-benzyloxy-5-methox...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin A recep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287193(1-Benzo[1,3]dioxol-5-ylmethyl-6-benzyloxy-5-methox...)
Affinity DataIC50: 2.50E+3nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article