BDBM50287192 1-Benzo[1,3]dioxol-5-ylmethyl-3-(3-methoxy-phenylsulfanyl)-6-propoxy-1H-indole-2-carboxylic acid::CHEMBL282398

SMILES CCCOc1ccc2c(Sc3cccc(OC)c3)c(C(O)=O)n(Cc3ccc4OCOc4c3)c2c1

InChI Key InChIKey=TWYHKSBHPXEEHI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287192   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287192(1-Benzo[1,3]dioxol-5-ylmethyl-3-(3-methoxy-phenyls...)
Affinity DataIC50: 6.70E+3nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287192(1-Benzo[1,3]dioxol-5-ylmethyl-3-(3-methoxy-phenyls...)
Affinity DataIC50: 590nMAssay Description:Inhibition of ET- 1 stimulated arachidonic acid release (AAR) in cultured rabbit renal vascular smooth muscle cells expressing the endothelin A recep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article