BDBM50287187 5-Benzyloxy-3-isopropoxy-benzo[b]thiophene-2-carboxylic acid::CHEMBL10143

SMILES CC(C)Oc1c(sc2ccc(OCc3ccccc3)cc12)C(O)=O

InChI Key InChIKey=MFIHFDWJBWXRFD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50287187   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287187(5-Benzyloxy-3-isopropoxy-benzo[b]thiophene-2-carbo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Affinity for human endothelin B receptor expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287187(5-Benzyloxy-3-isopropoxy-benzo[b]thiophene-2-carbo...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compound was evaluated for the receptor binding activity in rabbit artery vascular smooth muscle cells expressing Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287187(5-Benzyloxy-3-isopropoxy-benzo[b]thiophene-2-carbo...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compound was evaluated for binding affinity against human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287187(5-Benzyloxy-3-isopropoxy-benzo[b]thiophene-2-carbo...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compound was evaluated for binding affinity against rabbit Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287187(5-Benzyloxy-3-isopropoxy-benzo[b]thiophene-2-carbo...)
Affinity DataIC50: 8.80E+3nMAssay Description:Affinity for human endothelin A receptor expressed in Ltk cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287187(5-Benzyloxy-3-isopropoxy-benzo[b]thiophene-2-carbo...)
Affinity DataIC50: 8.80E+3nMAssay Description:Compound was evaluated for binding affinity against human Endothelin A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article