BDBM50287002 6-(3-Dimethylamino-phenyl)-4-hydroxy-3-(2-isopropyl-phenylsulfanyl)-pyran-2-one::CHEMBL12884

SMILES CC(C)c1ccccc1Sc1c(O)cc(oc1=O)-c1cccc(c1)N(C)C

InChI Key InChIKey=XKMJUHMILMFKLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287002   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50287002(6-(3-Dimethylamino-phenyl)-4-hydroxy-3-(2-isopropy...)
Affinity DataIC50: 114nMpH: 4.7Assay Description:Inhibitory activity against purified HIV-1 protease (BH10) at a pH of 4.7 and a final enzyme concentration of 0.45-1.1 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article