BDBM50286906 (2S,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl)-2-phenoxymethyl-pentanoic acid::CHEMBL34884

SMILES OC(=O)CNC(=O)[C@@H](C[C@@H](COc1ccccc1)C(O)=O)Cc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=CXWNRJVOFAKQLW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50286906   

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50286906((2S,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP) from rat kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286906((2S,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibition of Neutral EndopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50286906((2S,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Affinity DataIC50: 5.90nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP) from rat kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetNeprilysin(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50286906((2S,4S)-5-Biphenyl-4-yl-4-(carboxymethyl-carbamoyl...)
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibition of neutral endopeptidase from rat kidney.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article