BDBM50286794 2-{[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoylamino}-3-(1-methyl-1H-indol-3-yl)-propionylamino]-methyl}-thiazole-4-carboxylic acid::CHEMBL352929

SMILES CC(C)C[C@H](NC(=O)N1CCCCCC1)C(=O)N[C@H](Cc1cn(C)c2ccccc12)C(=O)NCc1nc(cs1)C(O)=O

InChI Key InChIKey=MPZZEJMYDNCQMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50286794   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286794(2-{[(R)-2-{(S)-2-[(Azepane-1-carbonyl)-amino]-4-me...)
Affinity DataIC50: 1.10E+3nMAssay Description:Binding affinity against ETA receptor from dog spleen membranes using [125I]ET1 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article