BDBM50286614 CHEMBL155943::CHEMBL3143473::Sodium; 2-[2-{2-[(2,6-dimethyl-piperidine-1-carbonyl)-amino]-4,4-dimethyl-pentanoylamino}-3-(1-methoxymethyl-1H-indol-3-yl)-propionylamino]-hexanoate

SMILES CCCC[C@@H](NC(=O)[C@@H](Cc1cn(COC)c2ccccc12)NC(=O)[C@H](CC(C)(C)C)NC(=O)N1[C@@H](C)CCC[C@H]1C)C([O-])=O

InChI Key InChIKey=VUMPRRVUQQKTMC-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286614   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286614(Sodium; 2-[2-{2-[(2,6-dimethyl-piperidine-1-carbon...)
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonistic activity against endothelin A (ETA) receptor using human neuroblastoma cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50286614(Sodium; 2-[2-{2-[(2,6-dimethyl-piperidine-1-carbon...)
Affinity DataIC50: 1.20nMAssay Description:Antagonistic activity against endothelin B (ETB) receptor using human girardi heart cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article