BDBM50286577 CHEMBL4174058

SMILES ONC(=O)CCCCCCN(Cc1ccc(F)cc1)c1ncc(s1)C(=O)NCc1cccnc1

InChI Key InChIKey=DGKUZYZFJOZWGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286577   

TargetHistone deacetylase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50286577(CHEMBL4174058)
Affinity DataIC50: 95nMAssay Description:Inhibition of recombinant full length human C-terminal His/flag-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2020
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50286577(CHEMBL4174058)
Affinity DataIC50: 470nMAssay Description:Inhibition of NAMPT (unknown origin) using NAM as substrate incubated for 5 mins followed by substrate addition measured after 15 mins by fluorometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2020
Entry Details Article
PubMed