BDBM50286481 CHEMBL4162202

SMILES ONC(=O)c1ccc(CN(Cc2ccc(F)cc2)c2ncc(s2)C(=O)NCCCn2ccnc2)cc1

InChI Key InChIKey=ROEPGCSNAWAJRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286481   

TargetHistone deacetylase 1(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50286481(CHEMBL4162202)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant full length human C-terminal His/flag-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells after 30 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2020
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50286481(CHEMBL4162202)
Affinity DataIC50: 14nMAssay Description:Inhibition of NAMPT (unknown origin) using NAM as substrate incubated for 5 mins followed by substrate addition measured after 15 mins by fluorometri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2020
Entry Details Article
PubMed