BDBM50286424 CHEMBL4170186

SMILES CNC(=O)Nc1ccc2c(CC[C@@]22OC(=O)N(CC(=O)N(Cc3ccccc3)[C@H](C3CC3)C(F)(F)F)C2=O)c1

InChI Key InChIKey=SGNUOADKIKQBIW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50286424   

LigandPNGBDBM50286424(CHEMBL4170186)
Affinity DataIC50: 45nMAssay Description:Inhibition of p300/CBP in human PC3 cells assessed as reduction in acetylated H3K27 levels after 3 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50286424(CHEMBL4170186)
Affinity DataIC50: 32nMAssay Description:Inhibition of p300/CBP (unknown origin) using biotinylated synthetic Histone H4 Peptide as substrate pretreated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2020
Entry Details Article
PubMed