BDBM50286121 1-[(R)-5-(4-Methyl-piperazin-1-yl)-2-oxo-1-propyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-3-m-tolyl-urea::CHEMBL318360

SMILES CCCN1c2ccccc2C(=N[C@@H](NC(=O)Nc2cccc(C)c2)C1=O)N1CCN(C)CC1

InChI Key InChIKey=HIDXDIXMVZDVNO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50286121   

LigandPNGBDBM50286121(1-[(R)-5-(4-Methyl-piperazin-1-yl)-2-oxo-1-propyl-...)
Affinity DataIC50: 2.70nMAssay Description:Compound was tested for its binding affinity against gastrin receptor in guinea pig gastric glandsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetCholecystokinin receptor type A(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50286121(1-[(R)-5-(4-Methyl-piperazin-1-yl)-2-oxo-1-propyl-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [125I]-BH CCK-8S from Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM50286121(1-[(R)-5-(4-Methyl-piperazin-1-yl)-2-oxo-1-propyl-...)
Affinity DataIC50: 7.60nMAssay Description:Compound was tested for its binding affinity by measuring the displacement of [125I]-BH CCK-8S from Cholecystokinin type B receptor in guinea pig cor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article