BDBM50285775 CHEMBL4159308

SMILES [H][C@@]12CN(C[C@]1([H])[C@H]2CNC(=O)c1ccc2[nH]c(=O)oc2c1)C(=O)OCC1CCCN(C1)C(=O)OC(C)(C)C

InChI Key InChIKey=JDALEHPCRNASDD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50285775   

TargetAutotaxin(Rat)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285775(CHEMBL4159308)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant rat ATX using LPC 18:1 as substrate after 2 hrs by rapidfire/MS-based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2020
Entry Details Article
PubMed
TargetAutotaxin(Rat)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285775(CHEMBL4159308)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of ATX in rat whole blood using LPA 17:0 as substrate after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50285775(CHEMBL4159308)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2020
Entry Details Article
PubMed