BDBM50285770 5-alpha-hydroxyacid imidazolyl biphenyl sulfonyl urea analogue::CHEMBL316021

SMILES CCCCc1nc(SC)c(n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1)C(C)(O)C(O)=O

InChI Key InChIKey=RQNPAXNBHPAQKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285770   

TargetType-2 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285770(5-alpha-hydroxyacid imidazolyl biphenyl sulfonyl u...)
Affinity DataIC50: 3.90nMAssay Description:In vitro binding affinity at Angiotensin II Type 2 receptor in rabbit uterus membrane by [125I]AII displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM50285770(5-alpha-hydroxyacid imidazolyl biphenyl sulfonyl u...)
Affinity DataIC50: 0.5nMAssay Description:In vitro binding affinity at Angiotensin II Type 1 receptor in rat liver membrane by [125I]AII displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article