BDBM50285668 2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propoxy}-phenyl)-1H-benzoimidazole::CHEMBL313620

SMILES COc1ccccc1N1CCN(CCCOc2ccc(cc2)-c2nc3ccccc3[nH]2)CC1

InChI Key InChIKey=WWABSSMRPUCUEJ-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50285668   

TargetD(3) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50285668(2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-prop...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to dopaminergic D3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50285668(2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-prop...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity towards cloned human Dopamine D3 receptor in CHO cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetD(3) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50285668(2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-prop...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetD(2) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50285668(2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-prop...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity to dopaminergic D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50285668(2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-prop...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity towards cloned human Dopamine D2 receptor in CHO cells using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50285668(2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-prop...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetD(2) dopamine receptor(Rat)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50285668(2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-prop...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]spiperone from dopaminergic D2 receptor in rat striatum homogenates after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50285668(2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-prop...)
Affinity DataKi:  109nMAssay Description:Displacement of [3H]ketanserine from 5-HT2A receptor in rat cerebral cortex homogenates after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50285668(2-(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-prop...)
Affinity DataKi:  258nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor in rat cerebral cortex homogenates after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed