BDBM50285563 (R)-2-((S)-1-((S)-4-methyl-1-oxo-1-(phenylamino)pentan-2-ylamino)-1-oxo-4-(4-(trifluoromethyl)phenyl)butan-2-ylamino)propanoic acid::(R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butylcarbamoyl)-3-(4-trifluoromethyl-phenyl)-propylamino]-propionic acid::CHEMBL310587

SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccc(cc1)C(F)(F)F)N[C@H](C)C(O)=O)C(=O)Nc1ccccc1

InChI Key InChIKey=CAZNRDJXNQISBA-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50285563   

Target72 kDa type IV collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285563((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)
Affinity DataKi:  110nMAssay Description:Inhibitory activity against human gelatinase-A (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285563((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)
Affinity DataKi:  830nMAssay Description:Inhibitory activity against human stromelysin-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285563((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)
Affinity DataKi:  832nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285563((R)-2-[(S)-1-((S)-3-Methyl-1-phenylcarbamoyl-butyl...)
Affinity DataKi:  5.10E+3nMAssay Description:Inhibitory activity against human collagenase (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article