BDBM50285503 CHEMBL76088::N-{[(2,6-isopropylphenyl)amino]carbonyl}dodecane-1-sulfonamide

SMILES CCCCCCCCCCCCS(=O)(=O)NC(=O)Nc1c(cccc1C(C)C)C(C)C

InChI Key InChIKey=SQTYAMAJWBEMLU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285503   

TargetAcyl-CoA:cholesterol acyltransferase(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50285503(N-{[(2,6-isopropylphenyl)amino]carbonyl}dodecane-1...)
Affinity DataIC50: 2.33E+3nMAssay Description:Inhibition of Acyl-CoA: Cholesterol Acyltransferase (ACAT) in intestinal microsomes of cholesterol fed rabbitsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50285503(N-{[(2,6-isopropylphenyl)amino]carbonyl}dodecane-1...)
Affinity DataIC50: 3.30E+3nMAssay Description:Compound at 5 uM concentration was tested in vitro for inhibition of Acyl-CoA: Cholesterol Acyltransferase (ACAT) in liver microsomes of cholesterol ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article