BDBM50285423 1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-ylsulfanyl]-pentyl}-2-methylsulfanyl-1H-benzoimidazole::CHEMBL51827

SMILES COc1ccc(cc1)-c1nc(SCCCCCn2c(SC)nc3ccccc23)[nH]c1-c1ccc(OC)cc1

InChI Key InChIKey=QTUMRUCNLVLQQC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285423   

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50285423(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes was measured by using AIV assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50285423(1-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50: 950nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article