BDBM50285415 CHEMBL4167184

SMILES CS(=O)(NCCNc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O)=NC#N

InChI Key InChIKey=SQYHDXKYNGEQTK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285415   

TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50285415(CHEMBL4167184)
Affinity DataIC50: 11nMAssay Description:Inhibition of IDO1 (unknown origin) after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50285415(CHEMBL4167184)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of IDO1 in human HeLa cells assessed as reduction in kynurenine productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed