BDBM50284883 2-(2-Dimethylamino-phenyl)-1-(7-hydroxy-4,4-diphenyl-hexahydro-thiopyrano[3,4-c]pyrrol-2-yl)-ethanone::CHEMBL41375

SMILES CN(C)c1ccccc1CC(=O)N1C[C@H]2[C@@H](C1)C(SC[C@@H]2O)(c1ccccc1)c1ccccc1

InChI Key InChIKey=YWNWTGILUQBCJO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284883   

TargetSubstance-P receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50284883(2-(2-Dimethylamino-phenyl)-1-(7-hydroxy-4,4-diphen...)
Affinity DataIC50: 77nMAssay Description:Compound was tested for its binding affinity to NK1 receptor in [3H]SP binding assay on rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284883(2-(2-Dimethylamino-phenyl)-1-(7-hydroxy-4,4-diphen...)
Affinity DataIC50: 370nMAssay Description:Compound was tested for its binding affinity to NK1 receptor in [3H]SP binding assay on human IM9 lymphoblasts cultured cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article