BDBM50284879 1-[7-Hydroxy-7-(2-methoxy-phenyl)-4,4-diphenyl-hexahydro-thiopyrano[3,4-c]pyrrol-2-yl]-2-(2-methoxy-phenyl)-propan-1-one::CHEMBL295845

SMILES COc1ccccc1[C@H](C)C(=O)N1C[C@H]2[C@@H](C1)C(SC[C@]2(O)c1ccccc1OC)(c1ccccc1)c1ccccc1

InChI Key InChIKey=WRYRNQFZXCNLIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284879   

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284879(1-[7-Hydroxy-7-(2-methoxy-phenyl)-4,4-diphenyl-hex...)
Affinity DataIC50: 38nMAssay Description:Compound was tested for its binding affinity to NK1 receptor in [3H]SP binding assay on human IM9 lymphoblasts cultured cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50284879(1-[7-Hydroxy-7-(2-methoxy-phenyl)-4,4-diphenyl-hex...)
Affinity DataIC50: 3.00E+3nMAssay Description:Compound was tested for its binding affinity to NK1 receptor in [3H]SP binding assay on rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article