BDBM50284878 2-[2-(2-Dimethylamino-phenyl)-acetyl]-4,4-diphenyl-hexahydro-thiopyrano[3,4-c]pyrrol-7-one::CHEMBL291146

SMILES CN(C)c1ccccc1CC(=O)N1CC2C(C1)C(SCC2=O)(c1ccccc1)c1ccccc1

InChI Key InChIKey=IEUUCAURFSXHRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284878   

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284878(2-[2-(2-Dimethylamino-phenyl)-acetyl]-4,4-diphenyl...)
Affinity DataIC50: 83nMAssay Description:Compound was tested for its binding affinity to NK1 receptor in [3H]SP binding assay on human IM9 lymphoblasts cultured cell line.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50284878(2-[2-(2-Dimethylamino-phenyl)-acetyl]-4,4-diphenyl...)
Affinity DataIC50: 41nMAssay Description:Compound was tested for its binding affinity to NK1 receptor in [3H]SP binding assay on rat brain membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article