BDBM50284716 5-bromo-7-oxo-(1S,2R)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL286395

SMILES OC(=O)[C@@H]1[C@@H]([C@H]2[C@@H]1c1ccccc1C(=O)c1cc(Br)ccc21)C(O)=O

InChI Key InChIKey=PTGZJENBFJFKND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284716   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284716(5-bromo-7-oxo-(1S,2R)-2,2a,7,11b-tetrahydro-1H-dib...)
Affinity DataIC50: 400nMAssay Description:Binding affinity towards cloned human ETA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284716(5-bromo-7-oxo-(1S,2R)-2,2a,7,11b-tetrahydro-1H-dib...)
Affinity DataIC50: 890nMAssay Description:Binding affinity towards cloned human ETB receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article