BDBM50284712 5-(3,5-dichlorophenyl)-7-oxo-(1R,2S)-2,2a,7,11b-tetrahydro-1H-dibenzo[a,e]cyclobuta[c]cycloheptene-1,2-dicarboxylic acid::CHEMBL286214

SMILES OC(=O)[C@@H]1[C@@H]([C@H]2[C@@H]1c1ccccc1C(=O)c1cc(ccc21)-c1cc(Cl)cc(Cl)c1)C(O)=O

InChI Key InChIKey=UUAWHNKOGOBWQF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284712   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284712(5-(3,5-dichlorophenyl)-7-oxo-(1R,2S)-2,2a,7,11b-te...)
Affinity DataIC50: 2.60E+4nMAssay Description:Binding affinity towards cloned human ETA receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284712(5-(3,5-dichlorophenyl)-7-oxo-(1R,2S)-2,2a,7,11b-te...)
Affinity DataIC50: 2.10E+3nMAssay Description:Binding affinity towards cloned human ETB receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article