BDBM50284642 CHEMBL283495::N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-4-oxo-3,4-dihydro-quinazolin-6-yl}-N-pyridin-3-ylmethyl-benzamide

SMILES Cn1nnnc1-c1ccccc1-c1ccc(Cn2cnc3ccc(cc3c2=O)N(Cc2cccnc2)C(=O)c2ccccc2)cc1

InChI Key InChIKey=QKLNRPZOAWUKDW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50284642   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50284642(N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)-biphenyl-4-yl...)
Affinity DataIC50: 1.70nMAssay Description:Binding affinity against AT1 receptor in rabbit aortaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284642(N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)-biphenyl-4-yl...)
Affinity DataIC50: 0.900nMAssay Description:Binding affinity against AT1 receptor in human adrenal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50284642(N-{3-[2'-(1-Methyl-1H-tetrazol-5-yl)-biphenyl-4-yl...)
Affinity DataIC50: 0.300nMAssay Description:Binding affinity against AT1 receptor in rat adrenal tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article