BDBM50284444 CHEMBL15689::[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-propyl-phenoxy]-phenyl-acetic acid

SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(O)=O)c1ccccc1

InChI Key InChIKey=IFUYEJOQMQZCAE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50284444   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50284444([4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-y...)
Affinity DataIC50: 11nMAssay Description:Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50284444([4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-y...)
Affinity DataIC50: 47nMAssay Description:Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rat midbrain membrane (AT2 receptor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284444([4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-y...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human endothelin A (ETA) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50284444([4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-y...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of human endothelin B (ETB) receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article