BDBM50283992 CHEMBL4174116

SMILES C\C(=N\Nc1nc(cs1)-c1cccc(c1)[N+]([O-])=O)C1CC1

InChI Key InChIKey=FFDARHATSKPIMY-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50283992   

TargetAmine oxidase [flavin-containing] A(Human)
"G. D'Annunzio" University of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50283992(CHEMBL4174116)
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
"G. D'Annunzio" University of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50283992(CHEMBL4174116)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of recombinant human MAO-B using kynuramine as substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
"G. D'Annunzio" University of Chieti-Pescara

Curated by ChEMBL
LigandPNGBDBM50283992(CHEMBL4174116)
Affinity DataKi:  7.30nMAssay Description:Competitive inhibition of recombinant human MAO-B using kynuramine as substrate pre-incubated for 15 mins followed by 2 fold compound dilution for 24...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2020
Entry Details Article
PubMed